Marco's Skilarence thread

[Caroline]

I agree with Caroline, Marco. The efficacy of DMF seems tied to it dropping the lymphocyte count, as happened with Jim, Caroline and myself. Your body has the ability to compensate, which might be why it doesn't work for you. I believe that in the Netherlands patients will keep taking higher doses (Psorinovo) until it starts working or the side effects or other complications force cessation. That is what I did.

A shame you have to wait for another treatment.

Cheers

Yes, that was previously in the time that Psorinovo was still prescribed by doctors which have a more natural approach of looking at the patients as a whole “system”, so not only to the outside of a disease. In that time Psorinovo was developed and appeared to be working excellently and higher doses were possible, even up to 12, as it did not contain additives that were toxic (like there were in Fumaderm).
In that time, dermatologists did not prescribe Psorinovo at all, by them it was placed in the alternative corner, this totally against every research that was done at that time and the fact that Germany already was using Fumaderm for years.
They did envy the good results though.
As the result of some manipulations it was forced in the medical guidelines and insurance policies, that only dermatologists were allowed to prescribe DMF. (Bastards)
So finally after many years they started to prescribe Psorinovo (and some prescribed Fumaderm), which always has been and remained a drugstore prepared medication (not by hand, but with a machine). Lots of patients did very well on Psorinovo due to the enteric coating for the stomach and the slow release of the DMF in the intestines. The slow release made it possible to go up to 12 pills at least, which was not done by the dermatologists, as there minds were stuck into the max of 6 pills with Fumaderm, they still have not recovered from their mindstuckness.
Then Skilarence came to the market, which tries to push Psorinovo off market. They want the money of course. But Almirall made the colossal mistake to not make a slow release, which means that on average, 50% of the patients cannot cope with the side effects and they go back to Psorinovo, which is still being made and is still covered by the insurance.
(I don’t want to take your thread almost off topic, so I will stop now, but there is still lots more to tell about the life of DMF)