Tremfya user's - pros and cons

[Jessica]

Now into second full week after Tremfya injection. The extreme side effects have not resolved. My autoimmune disease is in full flare - I took pictures of 3 areas where I had plaque. One seems lighter - heading toward reaction I hope. The other 2 are very red and painful. My scalp has developed new plaque but I know that behind ears and scalp area are "easy" prey for psoriasis. My joint pain is more evident. I never had knee pain but I have it now. My fingers are tingling with pain (joint pain).  I'm extremely exhausted. One person in quiet if fatigue was present before Tremfya. Yes, I have had days where I am tired but the only time I ever felt this level of fatigue was day of and day after methotrexate dosing. This fatigue has me immobilized for most of the day. Still, my biggest concern is the constipation. In a word, OUCH!! I have taken Miramax to help the process but it's really not helping.
So my question of the manufacturer is should I take dose #2? Before that, actually, is there some "antidote" to take when feeling lousy after dose #1.
I'm not getting any real help. I'm hydrating, resting, limiting use of Advil and Tylenol. 
There's my update. Curious if any others using Tremfya have had similar reactions? Did you improve after dose #2? 
Thanks for your help and compassion.
-Jessica