Newbie Chloe Mary :)

[Caroline]

Hi Cloe Mary,

Welcome to Psoriasisclub !

Andddd.... perhaps welcome to the DMF gang !

And very nice that you are from the Netherlands, as I am too.

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Concerning DMF/Skilarence
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There is a load of know how and experience on DMF right over here on Psoriasisclub and in the Netherlands, although experience with DMF with the dermatologists is limited. There is a real expert on DMF in the hospital in Zoetermeer.

Skilarence/DMF side effects are:

1. Flushes... you get all red for a while, mostly 20-30 minutes. Totally harmless but very important as it is a signal that the drug is working.
   
2. problems in the intestines, cramps may occur and/or tummy may get a bit unstable. No real problem, just perhaps inconvenient. After a while your tummy may get used to the drug just like with Jim.
   
3. Lowering of the lymphocytes. Also a signal that the drug is working, there is a publication about that (have to search where). This is the only serious side-effect. !Watch it! your lymphocytes may not become too low. Certainly not lower than 0.5, but the derm will keep an eye on that (where are you treated? btw)
   

Experience shows that problem 2 is the reason that a number of people will stop with this treatment. That is because DMF is irritating for the intestines. But... you are in the Netherlands...so there is an alternative called Psorinovo. IF you have the intestine problem request to have Psorinovo prescribed, as this will dilute very slowly in the intestine and thus with most patients this will have much less problems over there. 

Some do have problems with side effect 1, first time is a bit scary, but it is really harmless and is an important signal that it works. 

Any questions? Don't hesitate to ask. There is a specific thread on DMF over here: [split] Dimethylfumarates and Psoriasis
And over here in this post RE: Bill's pure dimethylfumarate thread there is a short description of the most probable reason that DMF works against psoriasis. 

Cheers, 
Caroline