Health Boards
Sun-30-05-2021, 21:19 PM
Yes, mixing with the yoghurt, simulates a bit the slower release of the DMF in your intestines.
The mistake that Almirall made when creating Skilarence, despite the advice of several well informed dermatologists, is they did not make it slow release.
Slow release reduces the side effects on two paths, 1. Less irritation of the intestines (apparently you don’t suffer from that) and 2. Reduce the diarrhoea effect, which basically signals that there is kind of an irritation of your intestines. If possible for you request to Almirall that they should produce a slow release version. (In modern terms this is called, “controlled” release, but that is just chique words window-dressing for what it in fact is… slow release. We have a slow release in the Netherlands, but that is not made by Almirall, lots of patient swear by it)
Myself, I would step back to 1x120 for a few days. Then retry the building up with intermittent 1x120 and the other day 2z120.
You could also do 1x120 in the morning and 1x120 in the evening, I don’t know how you take them now.
Effect on your psoriasis can take some time, the effect of DMF is probably that certain cytokines that cause your psoriasis inflammation are robbed by their trigger, so gradually production of them will be reduced and this will, if everything goes as planned, reduce your Psoriasis.
The mistake that Almirall made when creating Skilarence, despite the advice of several well informed dermatologists, is they did not make it slow release.
Slow release reduces the side effects on two paths, 1. Less irritation of the intestines (apparently you don’t suffer from that) and 2. Reduce the diarrhoea effect, which basically signals that there is kind of an irritation of your intestines. If possible for you request to Almirall that they should produce a slow release version. (In modern terms this is called, “controlled” release, but that is just chique words window-dressing for what it in fact is… slow release. We have a slow release in the Netherlands, but that is not made by Almirall, lots of patient swear by it)
Myself, I would step back to 1x120 for a few days. Then retry the building up with intermittent 1x120 and the other day 2z120.
You could also do 1x120 in the morning and 1x120 in the evening, I don’t know how you take them now.
Effect on your psoriasis can take some time, the effect of DMF is probably that certain cytokines that cause your psoriasis inflammation are robbed by their trigger, so gradually production of them will be reduced and this will, if everything goes as planned, reduce your Psoriasis.