Bill's pure dimethylfumarate thread

[Bill]

Time for an update. I continued with the 600 mg dose every other day until early August. The disease had been very stable to this point, so I decided to up the dosage to 800 mg every other day. This increase brought about a reduction in my disease to a Pasi below 0.5 within a few days. Mid August I caught a cold and ceased taking the drug for a week. I resumed at 800 mg every other day until catching a second cold around September 12. Concerned that the immunosuppression from this dosage may be too great, I ceased taking the drug and bought a binocular microscope on eBay and did some manual cell counts using a hemacytometer. This gave counts of around 5.5, with the lymphocyte count about 20% of this value. I was off DMF for about 2 1/2 weeks, with very little change in my disease, although near the end of this break I did notice the itchy angry feeling returning to my skin. As a precaution I decided to resume at a dosage of 800 mg every third day. The disease has been stable with this dosage, but has again been reducing over the past week or so. My hemacytometer is currently out of action with a broken cover slip and hopefully some cover slips ordered early October should arrive soon. I may cut the dosage to 800 mg every fourth day as a further precaution until I can do further counts, but I am feeling very well and I taking no painkillers for the mild arthritis. My Pasi currently sits below 0.4.

Cheers,

Bill