Methotrexate Injection

[Fred]

When I was on 10 little pills of methotrexate I took them on a Monday and a 5mg folic acid tablet on the Friday .... Agree with Dave it's so your folate levels don't  fall... But I have no idea what the levels should be

When I was on them in the UK they never gave me any folic, and they wondered why I stopped going to my dermatology appointments.  

A study investigating folate levels in methotrexate patients with rheumatoid arthritis concluded that there is a close relationship between folate status and side-effects during methotrexate therapy and that only a minority of side-effects are reported when concomitantly measured Red Cell Folate levels are above 600 – 800 nmol/l

Raised levels of homocysteine are associated with coronary heart disease and stroke .  Homocysteine levels are frequently elevated in rheumatoid arthritis patients and low dose methotrexate treatment may increase them further .  Folic acid supplementation lowers the prevalence of chronic hyperhomocysteinemia .  

A little bit more info Fred.

Not sure if it's good info for me though Dave.

I knew I hated this bloody stuff, so not only does it poison me, it can also cause my ticker to go wonky.