Health Boards
Sat-17-11-2012, 13:12 PM
Ok here we go....
I have tried to keep this brief and if there are any questions please, please ask.
I have left out the Sponsors name and the code reference to the product.
The product has been given to more than 2500 in other studies of psoriasis, rheumatoid arthritis, inflammatory bowl disease and dry eye.
I am one of 660 patients in 12 countries being asked to take part in the study because I have chronic plaque psoriasis. I am one of 50 patients in the UK. The study is over a period of 56 weeks.
I am currently in phase 3 of a mixed blind treatment, withdrawal and re-treatment study of 2 oral doses in subjects with moderate to severe plague psoriasis.
The product is a blocker of an enzyme called "Janus Kinase"' which acts like a gate into the cells of the immune system ( our body's defence against infection). By blocking the enzyme, the cells of the immune system are expected to produce fewer chemicals believed to cause psoriasis.
The study is looking at the good and bad effects. I attend a Hospital clinic every 4 weeks. I give several blood samples and have a full health scan including an inspection of my skin condition. Periodically I have full ECG etc. Apart from checking my vitals the study monitors blood, urine, my genes (DNA),RNA, proteins and metabolises.
During the study I am not allowed to use any other form of treatment or spend time in sunlight.
I keep a diary of my doses and I have a questionnaire at each clinic which asks about my mental and emotional state, if there are any restrictions on my work, study, sex life and general social being.
I took photos on the first day of my treatment ( I have no problems at anyone seeing them ) which when I work out how to upload etc.
The product is not a cure but it is a suppressor. At this moment in time ( week 44) my skin is 100% clear and yes I look sexy again
I feel good about myself but not confident enough to go shopping in a mankini just yet.
I will give out more info as I progress into the extension study.
So for now folks..... There is hope x
Thadius
I have tried to keep this brief and if there are any questions please, please ask.
I have left out the Sponsors name and the code reference to the product.
The product has been given to more than 2500 in other studies of psoriasis, rheumatoid arthritis, inflammatory bowl disease and dry eye.
I am one of 660 patients in 12 countries being asked to take part in the study because I have chronic plaque psoriasis. I am one of 50 patients in the UK. The study is over a period of 56 weeks.
I am currently in phase 3 of a mixed blind treatment, withdrawal and re-treatment study of 2 oral doses in subjects with moderate to severe plague psoriasis.
The product is a blocker of an enzyme called "Janus Kinase"' which acts like a gate into the cells of the immune system ( our body's defence against infection). By blocking the enzyme, the cells of the immune system are expected to produce fewer chemicals believed to cause psoriasis.
The study is looking at the good and bad effects. I attend a Hospital clinic every 4 weeks. I give several blood samples and have a full health scan including an inspection of my skin condition. Periodically I have full ECG etc. Apart from checking my vitals the study monitors blood, urine, my genes (DNA),RNA, proteins and metabolises.
During the study I am not allowed to use any other form of treatment or spend time in sunlight.
I keep a diary of my doses and I have a questionnaire at each clinic which asks about my mental and emotional state, if there are any restrictions on my work, study, sex life and general social being.
I took photos on the first day of my treatment ( I have no problems at anyone seeing them ) which when I work out how to upload etc.
The product is not a cure but it is a suppressor. At this moment in time ( week 44) my skin is 100% clear and yes I look sexy again
I feel good about myself but not confident enough to go shopping in a mankini just yet. I will give out more info as I progress into the extension study.
So for now folks..... There is hope x
Thadius