Health Boards
Thu-11-06-2015, 09:32 AM
Hi all.
My view is that the tummy upset directly relates to the speed of tummy emptying. The slower the emptying, the worse the symptoms. And anything that gives reflux or taking DMF with gastic reflux is asking for trouble. I also hold the view that the anti-psoriatic effect of the drug relates to the peak plasma concentration of the DMF, whereas the wbc suppression relates to the total dosage. Were I to have continued at a dosage of 240 mg three times daily, my disease would have stabilised at around 5-10% plaque coverage and eventually a falling lymphocyte would have forced me to cease taking the drug. Changing the way I take the DMF has allowed me to continue to erode the disease whilst allowing my wbc to return to normal levels.
Of course, it should be noted that I am a guinea pig. Such a station can have its privileges.
Cheers,
Bill
My view is that the tummy upset directly relates to the speed of tummy emptying. The slower the emptying, the worse the symptoms. And anything that gives reflux or taking DMF with gastic reflux is asking for trouble. I also hold the view that the anti-psoriatic effect of the drug relates to the peak plasma concentration of the DMF, whereas the wbc suppression relates to the total dosage. Were I to have continued at a dosage of 240 mg three times daily, my disease would have stabilised at around 5-10% plaque coverage and eventually a falling lymphocyte would have forced me to cease taking the drug. Changing the way I take the DMF has allowed me to continue to erode the disease whilst allowing my wbc to return to normal levels.
Of course, it should be noted that I am a guinea pig. Such a station can have its privileges.
Cheers,
Bill