Fumaderm - questions.

[jiml]

Hi all.

My view is that the tummy upset directly relates to the speed of tummy emptying. The slower the emptying, the worse the symptoms. And anything that gives reflux or taking DMF with gastic reflux is asking for trouble. I also hold the view that the anti-psoriatic effect of the drug relates to the peak plasma concentration of the DMF, whereas the wbc suppression relates to the total dosage. Were I to have continued at a dosage of 240 mg three times daily, my disease would have stabilised at around 5-10% plaque coverage and eventually a falling lymphocyte would have forced me to cease taking the drug. Changing the way I take the DMF has allowed me to continue to erode the disease whilst allowing my wbc to return to normal levels.

Of course, it should be noted that I am a guinea pig. Such a station can have its privileges.

Cheers,

Bill

You could well be right with your reckoning, you certainly have kept records on here of the effects different dosing regimes have worked for you, and I think you are right there is some merit in taking larger spaced out doses to give your blood time to recuperate.
I don't think it would work with Fumaderm though because of the added salts, but may well work on a pure DMF tablet like psorinovo.
Thanks again for keeping us up to date on your progress
Being a guinea pig has privileges as long as you are careful, and not a step to be taken lightly