decreased MTX effectiveness

[jiml]

I have been on a regimen of 0.8 ml MTX (20mg/ml) weekly to control my plaque Psoriasis. It has been wonderful and basically left me symptom free for 4 yrs . Recently I have noticed some recurrence of scalp issues....
I have monitoring labs every 8 wks, and all has remained "normal".
Anyone have any info on relapse in the face of ongoing treatment?
thanks.

Hi and    to the forum, I'm sure you will get answers to this question from some of our members, but myself I can't help, as I gave up on methotrexate before it stopped working, I was on 10x2.5mg tablets when I changed treatments because I couldn't handle the side effects I was getting.

So firstly can you think of anything that may have triggered it... For instance a stressful occurance or bad throat infection, as they are among the many things that can trigger an episode.

Or if not have you considered raising your dose to gain control again ( check with your dermatologist before you do that)
That's all I can think of at present but look through the Heath boards or put Methotrexate in the search facility at the top of the page and see what comes up.

Many of our members are from Europe and you are not likely for them to see your post till morning, but may well hear from other parts of the world......meantime make yourself comfortable, and check out the rest of the forum or visit the off topic boards where members often linger and enjoy a joke together or just to chat if you wish
Welcome again and hope you soon get some answers