Systemic treatment rotation

[JohnB]

This thought has been mulling around the cavernous void of my head for a while now and peoples experience on this forum have only made me question;
Most people as far as I can tell end up falling out with each drug in turn as the body gets used to it. Is there any milage in cycling through a couple of drugs on an x month rotation to avoid tolerance (I am assuming a short delay to purge the body and compatibility).
I do wonder? Or am I barking up the wrong tree?

Answers on the back of a postage stamp please