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Psoriasis Club › HealthHealth Boards › Psoriasis In The News v
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Taltz (ixekizumab) gets EU approval for Psoriasis

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Taltz (ixekizumab) gets EU approval for Psoriasis
Caroline Offline
You must hurry if you ever want to catch a chicken...
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Forum Helper
Posts: 26,589
Threads: 113
Joined: Nov 2011
Gender: Female
Location: In between the tulips
Psoriasis Score: 3
Psoriatic Arthritis Score: 3
PQOLS: 4
Treatment: Got back to DMF slow release
#7
Wed-27-04-2016, 17:54 PM (This post was last modified: Wed-27-04-2016, 18:01 PM by Caroline.)
Interesting this also heads for IL-17, like cosentyx. This receptor may thus be an important one in the area of psoriasis.

Quote from a study:
Quote:
We also analyzed direct changes in cytokine production in response to anti-CD3 stimulation (0.5 μg/ml for 24 h) with 10 μM DMF or vehicle using ELISPOT technology. This showed a significantly reduced production of IL-2 and IL-17, but no changes in IL-4 and IL-5 in C57BL6 splenocytes (Figure 3C) and a reduction in IL-2, IL-4, IL-5, IL-6, and IL-17 production in SJL splenocytes

So it also seems that DMF is doing something with all those IL's. Big Grin But this is a study on mice.
Why does that me make me think of Jim ? Huh
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Messages In This Thread
Taltz (ixekizumab) gets EU approval for Psoriasis - by Fred - Wed-27-04-2016, 14:01 PM
RE: Taltz (ixekizumab) gets EU approval for Psoriasis - by jiml - Wed-27-04-2016, 14:18 PM
RE: Taltz (ixekizumab) gets EU approval for Psoriasis - by mabcomp - Thu-09-06-2016, 23:26 PM
RE: Taltz (ixekizumab) gets EU approval for Psoriasis - by jiml - Thu-09-06-2016, 23:47 PM
RE: Taltz (ixekizumab) gets EU approval for Psoriasis - by Grizzly Bear - Wed-27-04-2016, 15:23 PM
RE: Taltz (ixekizumab) gets EU approval for Psoriasis - by Fred - Wed-27-04-2016, 16:08 PM
RE: Taltz (ixekizumab) gets EU approval for Psoriasis - by jiml - Wed-27-04-2016, 16:17 PM
RE: Taltz (ixekizumab) gets EU approval for Psoriasis - by Fred - Wed-27-04-2016, 16:22 PM
RE: Taltz (ixekizumab) gets EU approval for Psoriasis - by Caroline - Wed-27-04-2016, 17:54 PM
RE: Taltz (ixekizumab) gets EU approval for Psoriasis - by Fred - Wed-22-06-2016, 15:34 PM
RE: Taltz (ixekizumab) gets EU approval for Psoriasis - by mabcomp - Wed-22-06-2016, 17:52 PM

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