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Nanofiber patch for psoriasis

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Nanofiber patch for psoriasis
Fred Offline
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#1
News  Tue-12-11-2024, 16:29 PM
Researchers at the University of Copenhagen have developed a patch for easier and more effective treatment of psoriasis.

Quote:
We have developed a dry patch, which contains active ingredients for treatment of psoriasis, and which reduces the frequency of use to once a day. It has the potential to make treatment more comfortable for psoriasis patients.

The patch is designed to contain two active ingredients at once and release them onto the skin at different rates.

The two ingredients are released in a controlled manner and at different rates, as they serve different functions: Salicylic acid is released immediately to remove the dead cells that have accumulated on the skin, while hydrocortisone decreases inflammation of the skin – a process that takes more time.

We have tested the prototype on pig skin and human skin cells and compared the results to the creams and ointments available at pharmacies, and our studies show that the patch is just as effective as standard treatments.

The researchers used electrospinning to produce the patch – a method where high voltage is applied to a polymer solution to produce synthetic nanofibers. The fibres are then used to make a fibre mat that may be attached to the skin like a plaster.

The researchers are still working on the patch. More research, product development and clinical trials are needed before the method is ready for use.

Source: ku.dk
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Caroline Offline
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#2
Tue-12-11-2024, 21:51 PM
The idea seems logical, but may have drawbacks. The patch must be oxygen transparent as a closed patch is not so good for your skin.

But it might be more comfortable than ointments.

Though the statement “ our studies show that the patch is just as effective as standard treatments.”does not give the idea that it is anyhow better.

So for now it is only the comfort aspect that may be interesting.
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Fred Offline Author
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#3
Tue-12-11-2024, 22:13 PM
Good points, plus my first thoughts were it would need to be one hell of a big patch to help most people. Yes a tiny bit of psoriasis, but as most of us know it soon gets worse.

I can see it may help a person having a small flare after another treatment, for example I can get a tiny bit on one hand but let's be honest full blown psoriasis it aint going to help with so twice daily cream seems easier to me.
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Caroline Offline
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#4
Tue-12-11-2024, 22:22 PM
(Tue-12-11-2024, 22:13 PM)Fred Wrote: Good points, plus my first thoughts were it would need to be one hell of a big patch to help most people. Yes a tiny bit of psoriasis, but as most of us know it soon gets worse.

I can see it may help a person having a small flare after another treatment, for example I can get a tiny bit on one hand but let's be honest full blown psoriasis it aint going to help with so twice daily cream seems easier to me.

Indeed… it really makes no sense for serious psoriasis.
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Turnedlight Offline
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#5
Wed-13-11-2024, 10:35 AM (This post was last modified: Wed-13-11-2024, 10:35 AM by Turnedlight.)
Does salicylic acid sting? I don’t think I’ve ever used it, I don’t tend to get particularly thick patches, just flakey areas.
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Fred Offline Author
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#6
Wed-13-11-2024, 12:28 PM
(Wed-13-11-2024, 10:35 AM)Turnedlight Wrote: Does salicylic acid sting? I don’t think I’ve ever used it, I don’t tend to get particularly thick patches, just flakey areas.


Don't know, I've never tried it.
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Kat Offline
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#7
Wed-13-11-2024, 21:15 PM
I guess it can:

Salicylic acid preparations are usually well tolerated, but mild stinging may occur especially on broken skin and when higher concentrations are used.


Not sure about a patch. I had a .. boil I think it was on my thigh. It was a bit painful and rubbing against clothing was uncomfortable so I put an adhesive bandage on it. When I went to remove, I actually pulled some skin off with it! My skin was quite dry but I didn't want to put lotion or anything where it wouldn't stick. I had never had that happen before. So I replaced with a different adhesive that I KNEW wouldn't bother me and although it didn't pull skin it off, it also didn't want to come off easily. So........... dry skin and adhesive is probably a no. Confused
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Fred Offline Author
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#8
Wed-13-11-2024, 21:21 PM
Another good point Kat, adhesive plasters can in my opinion make things worse when you peel them off.  I think they have more work on their hands than they first thought, can't help thinking they should ask people with psoriasis before going further.  91

*But not on here as we are independent, so please don't join to do so.  Wink
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Kat Offline
Take my advice; I don't use it anyway.

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#9
Wed-13-11-2024, 21:24 PM
(Wed-13-11-2024, 21:21 PM)Fred Wrote: Another good point Kat, adhesive plasters can in my opinion make things worse when you peel them off.  I think they have more work on their hands than they first thought, can't help thinking they should ask people with psoriasis before going further.  91

*But not on here as we are independent, so please don't join to do so.  Wink

Snigger
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