Medications and Biologics

[Caroline]

I see Fred's already replying. Think that will clear up and give information.
Maybe I will add to that later.

Thanks Caroline, I think you understand a lot of the scientific stuff associated with these meds. Admittedly, I don't have that understanding.

Hi Kat,

Certainly I can tell you why I think my treatment works, but instead of that I can better point you to my thread on "Dimethylfumarates and psoriasis" starting at post Dimethylfumarates and Psoriasis. Over there is a quite follow able explanation.

In short.
Psoriasis is an immune disease.
You can do anything to fight the effects on the skin, but basically that don't work as you don't get to the origin. The origin is the immune system.
30-35 years ago, dr. Schweckendieck did a lot of research on dimethylfumarates. He did this because of his knowledge of the human energy system, the energy cycle in our cells.
In the skin cells, the energy cycle is going too fast, so the cells live and die in a to high speed.
Therefore you get all those plaques and so on.
An essential part of the energy cycle of your cells are fumarates. Dr. Schweckendieck found that with people with psoriasis there was a problem with this cycle. He himself had psoriasis also.
He created the ester of Fumaric acid, called dimethyfumarate. This ester has its influence in the energy system, and so to say, more or less repairs this cycle. There is very much medical stuff behind this simple explanation, all kind of chemical reactions take place of course.
The result anyway is that the cells restore there energy cycle, ones temperature raises slightly, and the result of that is again that the problems with your skin, but also problems with psoriatic arthritis, disappear.
Dr. Schweckendieck tried everything on himself, with bare DMF, like Bill does. And it is amazing that he found that this works.
In the history of DMF it even appears that it works for 70-75% of the population of psoriasis sufferers, these are numbers from dr. Kunst who treated a few thousand patients. This while the side effects are quite limited, certainly compared to MTX which is pure poison.
In fact DMF should be one of the first non-biologicals to try (DMF is not a biological), but current medicine is very old fashioned and refuses to look over their borders. Though a recent seminar presented the new protocol and DMF went up quite in the ranks. Dr. Schweckendieck was very neglected because common medical researchers did not believe that such a simple doctor could find something like this.
Currently interest in DMF is very quickly rising as some large pharma found out that it appears to work very well also for MS and Crohn's disease. So a lot of money can be gained.
Fumaderm and Psorinovo are the modern versions of the DMF tablets. They both work quite well. Ask Jim and others.
There is a lot of information available. Your doctors could contact the Dutch patients community to find out more.

Did this answer a bit of your curiousity?
Caroline