Health Boards
Fri-02-01-2015, 08:34 AM
Hi Jaynie,
I agree with Jim.
Seen from the perspective that acetrecitin is not working and methotrexate also not, you have to move on and stop with these two. You are feeling ill and that is not a good sign.
There are two options now, as Jim says, the MAB (monoclonal anti bodies) direction, they specifically inhibit a relevant and small portion of your immune system. Only the part and that is relevant for psoriasis.
The other direction is the direction of the dimethylfumarates. Jim himself is on them, he uses Fumaderm.
Myself, if I would be you, think that it might be good to take the DMF-step in between going to the MAB's. Reasons are that the success rate of DMF is high, 70% chance that it works, it is cheap compared to the MAB's, it is quite harmless and has side effects that can be dealt with.
Going that route would mean that you still have the MAB's as a backup treatment.
My two cents in your difficult descision.
Anyway I think that almost everyone on the forum will be happy that you are off methotrexate.
Caroline
I agree with Jim.
Seen from the perspective that acetrecitin is not working and methotrexate also not, you have to move on and stop with these two. You are feeling ill and that is not a good sign.
There are two options now, as Jim says, the MAB (monoclonal anti bodies) direction, they specifically inhibit a relevant and small portion of your immune system. Only the part and that is relevant for psoriasis.
The other direction is the direction of the dimethylfumarates. Jim himself is on them, he uses Fumaderm.
Myself, if I would be you, think that it might be good to take the DMF-step in between going to the MAB's. Reasons are that the success rate of DMF is high, 70% chance that it works, it is cheap compared to the MAB's, it is quite harmless and has side effects that can be dealt with.
Going that route would mean that you still have the MAB's as a backup treatment.
My two cents in your difficult descision.
Anyway I think that almost everyone on the forum will be happy that you are off methotrexate.
Caroline