any known interactions with psoriasis drugs and recreational drugs?

[moggleflop]

Yeah, it makes me mad. It was the same for me with a mild episode of depression- I went to pretty much a warzone to volunteer with a grassroots group, came back a little messed up and "self-medicated" with hash. Went to the doctors to try and find some talking therapy and she refused, offering me all these crazy anti-depressants. With side effects like: 'may make your symptoms worse. can cause suicidal ideation' etc etc. Then had a go at me for smoking. Its insane.

With regards to the original question, I know ciclosporine affects the kidneys, and I know ketamin really isnt good for them either, so I will steer clear from that. I just dont know enough about the chemical reactions in the body to make any more guesses.

What was methotreate like?