Fumaderm after Ciclosporin

[Closed account 1259]

I am posting on behalf of my 76 year old husband. We are having a lot of problems controlling the psoriasis although we are seeing the dermatologist on a regular basis. Ciclosporin did work but sadly blood tests showed that it also affected the liver and kidney function. The Doctor then tried reducing the dose but this did not help. My husband has been started on Fumaderm and took his first tablet on Wednesday night. He felt very sick today but I realise that this might be a side affect and am going to encourage him to keep taking it. He is still on Acetretin because the dermo felt he needed the overlap to prevent flare ups. I would say that the flare ups have been very bad and he has had to have antibiotics due to the infections. He is having a lot of problems walking due to the skin on his heels peeling.
I just wondered how others coped with Fumaderm?  The Dermo did say that around a  third of people have to come off it due to the side affects.....
If it does not work, the next option is injections but my husband is very against these. Also he has anaemia which is being investigated and the dermo wanted to find the cause of the anaemia before going down this route. He also has Lupus which is thankfully dormant at the moment. I do now understand that some of the medications initially used to treat the Lupus may well have made the psoriasis worse or even sparked it.
Thank you for reading. I do feel very out of my depth trying to help my husband - I am his carer, and he does get quite depressed at times especially when he is really struggling to walk or get his shoes on.