Folic Acid overdose

[Fred]

I came on this site again because I thought if anyone could find anything out it would be you u or Fred.

Hello Cathy, I'm sorry I was unable to help but I don't have much experience of Folic Acid. However it does seem a high dose you are taking to me, but I'm only saying that because when I briefly tried methotrexate again I was on a 5Mg injection of methotrexate on Mondays and 5Mg of folic acid on Tuesdays. So as you are on 5Mg per day it just sounds a bit high to me. (But like I say my knowledge is minimal in regards to folic acid)  

I did find this statement if it helps:

Quote:

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No cases of acute overdosage appear to have been reported, but even extremely high doses are unlikely to cause harm to patients. No special procedures or antidote are likely to be needed.

Re: "What is this poison I am putting in my body?"

Folic acid (Folate) is Vitamin B9 it can be found in dark green leafy vegetables, fruits and fruit juices, nuts, beans, peas, dairy products, poultry and meat, eggs, seafood, grains. avocado, beetroot, spinach, liver, yeast, asparagus, brussel sprouts.

So it's not really a poison, and any excess in your body will be passed with urine as your body will not require it. Methotrexate can block access to folate so the folic acid is taken to compensate.

Yes your dermatologist does care and will work with you to find something that works. Having said that you need to be happy with your dermatologist and have a good relationship with them, so if you're not sure your dermatologist is looking after you correctly I would ask to see another one. It's your body, and you need to be happy to help treat psoriasis

I hope that has helped a bit, and I'm sorry I couldn't help more but like I said I'm no expert.

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I noticed you said you have tried Fumaderm and Acitretin before and now methotrexate is causing you problems so it could be time to push for one of the Bio treatments see here:  
Biological Treatments For Psoriasis

Regards.

Fred.

[dyorke]

Hi  Cathy

I recently started on MXT - I was prescribed 1 Folic acid tablet to be taken the day before taking the MXT dose.

Reason -  to counteract any sickness that 'may' be caused by the MXT

Tink x

[Turnedlight]

Hi Cathy!

Did you contact your derm / derm nurse to let them know you had this adverse reaction? I do remember from taking folic acid that it made me queasy but I would contact the derm and ask how to proceed.

[mataribot]

Most of use refer to MTX side effects as the zombjie effect. Another thing to try is drinking more before taking MTX and when you feel ok.

[Maryam]

I wouldn't call 5mg an overdose, your body should be able to be handling this very well. 


Some people need to take a lot more. I copied this from a medical website (don't know if this is allowed Fred...)

"Adults (over 18 years old)
General:The daily suggested intake levels of folic acid are as follows: males over 13 years, 400 micrograms; females over 13 years, 400-600 micrograms; pregnancy all ages, 400-600 micrograms; breastfeeding females of all ages, 500 micrograms. The maximum daily intake level of folic acid for people 19 years and older (including pregnant or breastfeeding women), 1,000 micrograms."

For anemia caused by folate deficiency, 1-5 milligrams has been taken by mouth daily until recovery.

For antiseizure drug-induced folate deficiency, 15 milligrams has been taken by mouth daily under the supervision of a qualified healthcare provider.

For bipolar disorder, 200 international units of folic acid has been taken by mouth daily for 52 weeks in patients stabilized on lithium. Three milligrams of folic acid have been taken by mouth daily for three weeks in patients starting valproic acid therapy.

For cancer (general), 0.2-40 milligrams of folate or folic acid (either taken alone or in combination with aspirin, vitamin B6, or vitamin B12) has been taken by mouth daily for 3-8 years, with mixed results.

For cognitive effects, 0.75-15 milligrams of folic acid has been taken by mouth daily for 1-36 months.

For colorectal cancer, 0.5-5 milligrams of folic acid has been taken by mouth daily for 3-8 years with mixed results.

For chronic kidney disease, 2-15 milligrams of folic acid has been taken by mouth daily, every other day or three times weekly, for a follow-up duration of 1-3.6 years.